Pathology reports offer a fairly accurate alternative to repeated testing in a central laboratory for determining estrogen receptor status in large epidemiologic studies of women with breast cancer. Read the rest of this entry »

This study is currently recruiting participants.
Verified by Biogen Idec, December 2007

Purpose

The goal of this clinical research study is to study the drug CNF2024 as a single agent or in combination with trastuzumab in patients with advanced breast cancer and to: Read the rest of this entry »

This study is currently recruiting participants.
Verified by National Cancer Institute (NCI), December 2007
Purpose

RATIONALE: Venlafaxine may be effective in relieving hot flashes caused by hormone therapy. Giving venlafaxine with zolpidem (a sleeping pill) may improve sleep and quality of life in women who are receiving hormone therapy for treatment or prevention of breast cancer. Read the rest of this entry »

This study is currently recruiting participants.
Verified by National Cancer Institute (NCI), April 2007

Purpose

RATIONALE: Drugs used in chemotherapy, such as methotrexate, cyclophosphamide, and liposomal doxorubicin, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Giving chemotherapy after surgery may kill any tumor cells that remain after surgery. It is not yet known whether giving liposomal doxorubicin after surgery is more effective than observation or cyclophosphamide and methotrexate in treating breast cancer.

PURPOSE: This randomized phase III trial is studying liposomal doxorubicin to see how well it works compared with observation or cyclophosphamide and methotrexate in treating older women who have undergone surgery for breast cancer.

http://clinicaltrials.gov/ct2/show/NCT00296010?term=breast+cancer&rank=8 

This study is currently recruiting participants.
Verified by National Cancer Institute (NCI), October 2007

Purpose

RATIONALE: Estrogen can cause the growth of breast cancer cells. Letrozole may fight breast cancer by lowering the amount of estrogen the body makes. It is not yet known which regimen of letrozole is more effective in postmenopausal women who have received hormone therapy for early-stage breast cancer.

PURPOSE: This randomized phase III trial is comparing two different regimens of letrozole in preventing cancer in postmenopausal women who have received 4-6 years of hormone therapy for hormone receptor-positive, lymph node-positive, early-stage breast cancer.

http://clinicaltrials.gov/ct2/show/NCT00553410?term=breast+cancer&rank=3 

Purpose

RATIONALE: Chemoprevention therapy is the use of certain drugs to try to prevent the development of cancer. Anastrozole may be effective in preventing breast cancer.

PURPOSE: This randomized clinical trial is studying how well anastrozole works in preventing breast cancer in postmenopausal women who are at increased risk for the disease.

http://clinicaltrials.gov/ct2/show/NCT00078832?term=breast+cancer&rank=2